Nicotine, an alkaloid extracted from tobacco plants.
Nicotine use results in rewarding effects on mood, cognition, stress and anxiety, facilitated by release of various neurotransmitters (ie, dopamine, norepinephrine, acetylcholine, glutamate, serotonin, GABA, endorphins).
| rise in the blood | 4–6 hours |
| day | plateau throughout the day |
| night | decline overnight |
| half-life | 2 hours |
| cross the BBB | 8 secs |
Constant nicotine exposure results in high risk of developing dependence symptoms, including tolerance and withdrawal.
consumer product
Little is known about the pharmacological and metabolic effects of R-nicotine in humans.
R-nicotine is a significantly less potent (~10-fold) agonist of nicotine receptors than S-nicotine.
1. Medical Background of Atomizers Atomization technology has long been applied in the medical field, particularly in the treatment of respiratory conditions such as asthma and COPD. By converting active compounds into ultra-fine particles, atomizers deliver substances directly to the lungs for rapid absorption and high bioavailability.
August 1st, 20251. Medical Background of Atomizers Atomization technology has long been applied in the medical field, particularly in the treatment of respiratory conditions such as asthma and COPD. By converting active compounds into ultra-fine particles, atomizers deliver substances directly to the lungs for rapid absorption and high bioavailability.
August 1st, 2025Introduction As healthcare providers in the U.S. increasingly seek effective, reimbursable methods to help patients quit smoking, water-based nicotine inhalation products are emerging as a powerful new solution. These formulations offer both clinical effectiveness and regulatory advantages—making them ideal for pharmacy and clinic distribution under Medicare-supported cessation programs. Medicare Covers Up to $2,000 Per Patient […]
July 23rd, 2025Introduction As healthcare providers in the U.S. increasingly seek effective, reimbursable methods to help patients quit smoking, water-based nicotine inhalation products are emerging as a powerful new solution. These formulations offer both clinical effectiveness and regulatory advantages—making them ideal for pharmacy and clinic distribution under Medicare-supported cessation programs. Medicare Covers Up to $2,000 Per Patient […]
July 23rd, 2025Abstract Oil-based cannabinoids have long faced challenges such as low oral bioavailability (typically under 15%), poor formulation compatibility, and inconsistent onset. Water-based delivery systems—THCX, and RENICO—offer a new standard of performance, combining faster absorption, enhanced versatility, and broader consumer appeal. This article outlines the science and innovation behind these next-generation cannabinoid formats. The Limitations of
July 18th, 2025Abstract Oil-based cannabinoids have long faced challenges such as low oral bioavailability (typically under 15%), poor formulation compatibility, and inconsistent onset. Water-based delivery systems—THCX, and RENICO—offer a new standard of performance, combining faster absorption, enhanced versatility, and broader consumer appeal. This article outlines the science and innovation behind these next-generation cannabinoid formats. The Limitations of
July 18th, 2025Abstract Inhalation drug delivery systems have been used in clinical practice for over half a century due to their efficient drug delivery properties. This paper systematically evaluates the pharmacological advantages of portable battery-powered nebulizers as a platform for cannabinoid inhalation. Studies indicate that, compared to traditional oral administration, the inhalation route via nebulization offers significant
July 4th, 2025Abstract Inhalation drug delivery systems have been used in clinical practice for over half a century due to their efficient drug delivery properties. This paper systematically evaluates the pharmacological advantages of portable battery-powered nebulizers as a platform for cannabinoid inhalation. Studies indicate that, compared to traditional oral administration, the inhalation route via nebulization offers significant
July 4th, 2025U.S. marijuana interest groups are sounding the alarm over a House Republican budget proposal that, if passed by Congress, would outright ban marijuana-derived THC products at the federal level, including so-called THCA flower. U.S. Rep. Andy Harris, a Maryland Republican who chairs a key subcommittee on the bill, said the proposal, the Agriculture, Rural Development,
July 6th, 2025U.S. marijuana interest groups are sounding the alarm over a House Republican budget proposal that, if passed by Congress, would outright ban marijuana-derived THC products at the federal level, including so-called THCA flower. U.S. Rep. Andy Harris, a Maryland Republican who chairs a key subcommittee on the bill, said the proposal, the Agriculture, Rural Development,
July 6th, 2025
